◾️Basal cell carcinoma ▪️Large basaloid lobules with peripheral nuclear palisade #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #bcc #basalcellcarcinoma #skintumors
🔬Pigmented basal cell carcinoma #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #bcc #skintumors
📌Papillary Renal cell Carcinoma •Usually circumscribed malignant neoplasm characterized by predominantly papillary or tubulopapillary architecture •Second most common type of kidney tumors in adults •Associated with trisomy or tetrasomy of 7/17 #microscopy -Predominantly papillary or tubulopapillary architecture -Lined by cells with variation of morphologies, ranging from small, basophilic cuboidal cells with inconspicuous nucleoli to large, eosinophilic cells with prominent nucleoli -Cells can be arranged in linear or a pseudostratified pattern -Psammoma bodies and hemosiderin pigments can be present #papillarycarcinoma #papillaryrenalcellcarcinoma #kidney #rcc #renaldisease #renalpathology #pathologylab #pathologynotes #histopath #neetpg #neetnotes #medstudent #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histology #pathologyskills #slide #slides #slidefordiagnosis #patho
Clear cell carcinoma of kidney •Most common renal epithelial tumor, accounting for ~2% of all malignancies, typically with clear cytoplasm and a compact nested or acinar growth pattern, intersected by delicate vasculature and with characteristic alterations to chromosome 3p involving VHL (von Hippel-Lindau) gene inactivation •Cortical mass with golden yellow variegated cut surface, with diverse architecture, primarily solid and nested #microscopy -Typically compact nests and sheets of cells with clear cytoplasm and distinct membrane -Network of arborizing small, thin walled vessels (important diagnostic feature for cases with granular eosinophilic cytoplasm) -Architectural patterns: solid, alveolar (nested), acinar (tubular), microcystic (containing extravasated red blood cells -Granular eosinophilic cytoplasm observed in high grade tumors or near areas of hemorrhage or necrosis #rcc #clearcellcarcinomaofthekidney #clearcellcarcinoma #renaldisease #renalpathology #pathologylab #pathologynotes #histopath #neetpg #neetnotes #medstudent #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histology# #pathologyskills #slide #slides #slidefordiagnosis #patho
🔺Malakoplakia 🔬Sheets of histiocytes with granular eosinophilic cytoplasm (von Hansemann cells) and basophilic intracytoplasmic inclusion (Michaelis-Gutmann bodies) #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #malakoplakia #michaeilgutmann
• ANA associated disorders nd their Immunofluorescence interpretations •The antinuclear antibody (ANA) is a defining feature of autoimmune connective tissue disease •ANAs are a class of antibodies that bind to cellular components in the nucleus, including proteins, DNA, RNA, and nucleic acid-protein complexes •ANA titers of less than or equal to 1:40 to 1:80 are considered negative #antinuclearantibodies #autoimunedisease #sle #rheumatoidarthritis #immunofluorescence #antigenantibodyreaction #sjorgenssyndrome #systemicsclerosis #labdiagnostic #path #pathologylab #pathologynotes #histopath #neetnotes #medstudent #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histology# #pathologyskills #inicet
▪️Castleman disease 🔬Hyalinized vessels in the center and thickened mantle zone with concentric (onion skin) pattern #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #lymphnode #castlemandisease
Pillole di dermatopatologia 🔬🦠 #anatomiapatologica #pathology #pathologylab #medicine #medstudent #unisi #siena #pathologistsassistant #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills
Win best Speaker Award!! Seize the opportunity to win Best Speaker Award at the 14th Emirates Pathology, Digital Pathology & Cancer Conference from December 17-19, 2024, in Dubai, UAE & Virtual. Register virtually here: https://pathology.universeconferences.com/virtual-registration/ #SurgicalPathology #Pathology #digitalpathology #SurgicalSpecimens #PathologyReports #Histopathology #Pathologists #DiagnosticPathology #CancerDiagnosis #MedicalLaboratory
🔵Menstrual phase endometrium🔵 🔬Endometrial stromal breakdown: dense round aggregates of stromal cells admixed with inflammatory cells and blood 🔬Papillary syncytial metaplasia is common #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #mensuralcycle #endometrium
🔬Herpes esophagitis #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #esophagus #herpesesophagitis #herpes
••Riedel thyroiditis/ -Riedel struma, / -fibrous thyroiditis/ -invasive thyroiditis •Rare disorder seen in elderly females •prototypical manifestation of IgG4-related disease group of fibro-inflammatory disorder. #gross -asymmetrical -stony hard -cuts with great resistance #microscopy -fibrous tissue completely replaces the area of the gland involved -fibrous tissue completely replaces the area of the gland involved -hyaline collagenization in the later stages -Inflammatory infiltrate can be quite prominent and usually consists of plasma cells (mostly IgG-4 producing), lymphocytes, and macrophages. -Numerous eosinophils may also be seen. #thyroid #thyroidpathology #path #pathologylab #pathologynotes #histopath #neetpg #neetnotes #medstudent #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histology# #pathologyskills #slide #slides #slidefordiagnosis #inicet
-Subacute thyroiditis/ granulomatous thyroiditis/ de Quervain thyroiditis •Granulomatous inflammation of the thyroid gland related neck pain and typically occurs a few weeks after a viral infection •1.Thyrotoxic phase: hyperthyroid (suppressed thyroid stimulating hormone [TSH] and elevated T4 and T3) due to follicle destruction and release of hormone 2.After 4 - 8 weeks: TSH and free T4 levels may be low #microscopy 1.Inflammatory infiltrate composed of multinucleated giant cells, foamy histiocytes, epithelioid histiocytes, neutrophils, lymphocytes, plasma cells 2.Early stage (acute; hyperthyroidism): -Follicular damage and loss of epithelium and colloid -Neutrophils, occasional microabscesses 3.Mid stage (hypothyroidism): -Chronic inflammation: lymphocytes, plasma cells -Epithelioid and nonepithelioid macrophages -multinucleated giant cells adjacent to follicles, engulf residual colloid 4.Late stage (resolution; recovery): -Fibrosis replaces destroyed follicles -Follicular tissue is regenerated #subacutethyroiditis #granulomatousthyroiditis# #thyroid #thyroidpathology #path #pathologylab #pathologynotes #histopath #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histology# #pathologyskills #slide #slides #slidefordiagnosis #neetpg #inicet #medstudent #pathologistsassistant #pathology
Abortion ❓Age of embryo… #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #embryo #abortion
♦️Ulcerative colitis/IBD 🔬Cryptitis (neutrophilic infiltration of crypt epithelium) 🔬Crypt abscess (crypt with intraluminal aggregates of neutrophils) 🔬Increased lymphoplasmacytic inflammation in the lamina propria 🔬Crypt architectural distortion (branched, dilated and disorganized crypts) #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #inflammatoryboweldisease #ulcerativecolitis
❓78 Y/O man / forehead skin lesion Diagnosis: Basal cell carcinoma #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #skin #basalcellcarcinomas
🦠Herpes simplex virus🦠 #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #cytology #papsmear #herpessimplexvirus
#hashimotothyroiditis Autoimmune disease presenting with goiter, elevated circulating antithyroid antibodies, often with hypothyroidism. Also known as Hashimoto disease, struma lymphomatosa, chronic lymphocytic thyroiditis, goitrous thyroiditis, lymphadenoid goitre #gross Diffuse symmetric enlargement of thyroid gland Cut surface: pale, yellow-tan, firm, nodular; resembles lymph nodes #microscopy Classic form: diffuse infiltration of thyroid parenchyma with lymphocytes and plasma cells; lymphoid follicle formation with germinal centers Atrophic thyroid follicles; many lined by oncocytic cells / oncocytes having abundant granular eosinophilic cytoplasm; rarely squamous metaplasia Polymorphic lymphocytic infiltrate, predominantly T cells. Elevated serum antithyroid antibodies Antithyroglobulin Anti-TPO Anti-TSH receptor #thyroid #thyroidpathology #path #pathologylab #pathologynotes #histopath #neetpg #neetnotes #medstudent #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histology# #pathologyskills #slide #slides #slidefordiagnosis #inicet
🟣Low grade squamous intraepithelial lesion (LSIL) 🙋🏻♀️Koilocyte #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #cytology #koilocytes #lsil
🔘High grade urothelial carcinoma of bladder 🔬Microscopic features: ▪️Fibrovascular cores lined by neoplastic urothelium ▪️Complex, solid to fused papillae common ▪️Architectural disorder; nuclear pleomorphism readily visible at low and intermediate power ▪️Crowded overlapping cells, dyscohesion common and partial denudation ▪️Nucleomegaly present, irregular and clumped chromatin ▪️Frequent prominent nucleoli and mitoses ▪️Inverted growth pattern may coexist (both exophytic and endophytic growth) #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #bladdermass #urothelialcarcinoma #highgradeurothelialcarcinoma
Cinquanta sfumature di ematossilina eosina #anatomiapatologica #pathology #pathologylab #medicine #medstudent #unisi #siena #pathologistsassistant #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #meningioma #psammomabodies #serouscarcinoma
⭕️Uterine leiomyoma⭕️ #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #uterinemyomata #leiomyom
🌀Serous borderline tumor ovary /Micropapillary subtype ❇️Micropapillary: ✏️Thread-like extensions lacking true fibrovascular cores, radiating directly from cyst walls or central bulbous and smooth contoured prominences with fibromatous / myxoid stroma ✏️Micropapillae appear 5 times longer than they are wide, resembling mythical snakes of Medusa’s head ✏️Low power appearance of labyrinthine spaces created by complex micropapillary interweaving #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #ovary #serousborderlinetumor
Call for Speaker!! Join us as a speaker and increase your visibility at the CME/CPD accredited 14th Emirates Pathology, Digital Pathology & Cancer Conference from Dec 17-19,2024 in Holiday Inn Dubai, Al Barsha, UAE & Virtual. WhatsApp us: https://wa.me/442033222718?text= Register virtually here: https://pathology.universeconferences.com/virtual-registration/ #Pathology #SurgicalSpecimens #PathologyReports #Histopathology #Pathologists #DiagnosticPathology #TissueDiagnosis #CancerDiagnosis #MedicalLaboratory #GrossPathology #MicroscopicPathology #PathologyCases #AnatomicPathology #ClinicalPathology
✨Endometrial polyp ✏️Polypoid shape, attenuated surface endometrium on 3 sides ✏️Large, thick walled blood vessels ✏️Fibrous stroma with spindled fibroblast-like cells, sometimes hyalinized ✏️Glandular architectural abnormality different from the surrounding endometrium, with cystic change, sometimes glandular crowding #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #endometrialpolyp
🔬Lower eyelid lesion #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills
🥦Paraovarian cyst 🔬 What’s your diagnosis… Diagnosis: Endometriotic cyst #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #ovary #fallopiantubes #paraovariancyst
⭕️Spindle cell lipoma ❇️Asymptomatic ❇️Longstanding, mobile lesion in subcutaneous tissue Usually solitary ❇️Shawl region of posterior neck / shoulder / upper back 🔬Microscopic features: ▪️Triad of mature adipocytes, bland spindle cells and hyalinized rope-like collagen fibers ▪️Myxoid background with mast cells frequent ▪️Short and stubby spindle cells show occasional palisading ▪️Rare lipoblasts present in half of case #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #lipoma #spindlecelllipoma
🖇️Chondrosarcoma 🔹Abundant cartilaginous matrix with chondrocytes embedded in lacunae 🔸Lobular or diffuse growth (depending on grade) Permeation of intertrabecular spaces 🔹Varying degrees of increased cellularity, nuclear atypia and mitotic activity 1️⃣Grade I: minimally increased cellularity, nodular growth and occasional binucleate nuclei 2️⃣Grade II: moderate cellularity and diffuse growth 3️⃣Grade III: high cellularity, marked atypical cells, pleomorphic appearance and easily identifiable mitotic figures #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #cartilage #chondrosarcoma
Call for Speaker!! It gives us great pleasure to invite you to at our 14th Emirates Pathology, Digital Pathology & Cancer Conference, CME/CPD recognized, December 17-19, 2024, in Dubai, UAE & Virtual. WhatsApp us: https://wa.me/442033222718?text= Register virtually here: https://pathology.universeconferences.com/virtual-registration/ #Pathology #SurgicalSpecimens #PathologyReports #Histopathology #Pathologists #DiagnosticPathology #TissueDiagnosis #CancerDiagnosis #MedicalLaboratory #GrossPathology #MicroscopicPathology #PathologyCases #AnatomicPathology #ClinicalPathology
▪️Myxopapillary ependymoma 💢A variably papillary architecture characterized by a radial arrangement of spindled or epithelioid to cuboidal cells around blood vessels with perivascular myxoid change and mucin rich microcyst formation ⤵️stains: ➕GFAP ➖Olig2 ➖EMA #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #braintumor #myxopapillaryependymoma
🧌Alveolar soft part sarcoma (ASPS) 📝Rare malignant mesenchymal neoplasm frequently composed of large, polygonal cells with abundant eosinophilic cytoplasm, a nested or pseudoalveolar growth pattern and PASD+ intracytoplasmic rhomboid or rod shaped crystals 🔖Most commonly seen in patients aged 15 , < 30 years ✂️Solid, nodular mass with fibrous bands and a rich blood supply 🔬Microscopic features: 🔘Large, round to polygonal cells with well defined cell borders 🔘Abundant eosinophilic granular cytoplasm 🔘Round, vesicular nucleus with a prominent nucleolus 🔘Organoid and nest-like growth pattern 🔘Central discohesion results in characteristic pseudoalveolar-like structures 🔘Lobules of tumor are divided by thick fibrous septa and rich capillary vascular network #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #softtissue #alveolarsoftpartsarcoma
International Day Of FAMILY👨👩👧👦🎉🥳 Some Togetherness, Some Laughs & A Lot Of Care Will Make A Great Family Day ! #togetherforever❤ . Best Pathology Laboratory in Mehsana. Get Tested Today For A Healthier Tomorrow ! . Experience Excellence In Diagnostic Services At The Best Pathology Laboratory In Mehsana, As We Take Pride As The Best Laboratory In Mehsana. . Branch 1 : B. K. In Front Of Cinema, Next To Mamta Medical, S.T. Workshop Road, Mehsana-384002 Branch 2 : Third Floor, M-3 Block, Hubtown, In Front Of New Bus Station, Dr. R. B. In Front Of Shah's New Hospital, Modhera Four Road, Mehsana-384002 We Offer The Convenience Of Home Sample Collection In Mehsana. For More Details Call Us At 99096 76024 | 02765 254096. #FamilyDay #FamilyFun #BondingTime #TogetherWeAreStronger #InternationalFamilyDay #familylove #familyfirst #familymatters #homesamplecollectionservice #fullbodycheckup #laboratory #mehsanacity #mehsana #mojilumehsana #madhuramlaboratory #BestLab #madhurampathologylab #best #service #bodytest #PathologyTesting #LabServices #PathologyReports #pathology #checkup #hubtownmehsana🤙🏻
તમારા આરોગ્ય ની સારવાર માટેનું BEST સરનામું એટલે મધુરમ પેથોલોજી લેબોરેટરી. #bestpathologyinmehsana . Get Tested Today For A Healthier Tomorrow ! Best Pathology Laboratory in Mehsana. . Experience Excellence In Diagnostic Services At The Best Pathology Laboratory In Mehsana, As We Take Pride As The Best Laboratory In Mehsana. . Branch 1 : B. K. In Front Of Cinema, Next To Mamta Medical, S.T. Workshop Road, Mehsana-384002 Branch 2 : Third Floor, M-3 Block, Hubtown, In Front Of New Bus Station, Dr. R. B. In Front Of Shah's New Hospital, Modhera Four Road, Mehsana-384002 We Offer The Convenience Of Home Sample Collection In Mehsana. For More Details Call Us At 99096 76024 | 02765 254096. #homesamplecollectionservice #fullbodycheckup #laboratory #mehsanacity #mehsana #mojilumehsana #madhuramlaboratory #BestLab #madhurampathologylab #best #service #bodytest #PathologyTesting #LabServices #PathologyReports #pathology #checkup #hubtownmehsana🤙🏻
Colon 🌀Solitary rectal ulcer 🔬Microscopic features: 🔹Superficial mucosal ulceration and villiform change 🔹Crypt hyperplasia and elongation with focal dilation (some glands diamond shaped) 🔹Fibromuscular hyperplasia of lamina propria 🔹Thickened muscularis mucosae with splayed fibers 🔹Ectatic capillaries 🔹Minimal inflammation #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #colon #solitaryrectalulcersyndrome
♦️cholangiocarcinoma with perineural invasion #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #perineuralinvasion #cholangiocarcinoma
🪁Chorangioma-Placenta 🌀Single or multiple well circumscribed spherical / oval masses if large enough to be grossly identifiable Subchorionic or marginal 🔬Microscopic features: ▪️Well circumscribed mass ▫️Fetal capillaries with surrounding stroma and trophoblast Infarction, fibrosis, hyalinization, calcification and hemosiderin deposition can be seen ▪️Trophoblast proliferation can be present but should not show cytological atypia #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #placenta #chorangiomaplacenta #chorangioma
🛸Solid pseudopapillary neoplasm-Pancreas ➰Low malignant potential tumors with unclear cell of origin and pathogenesis 📍Presents in younger women, classically as solitary body / tail mass 🙋🏻♀️F:M = 10:1 (accounts for 30% tumors in < 40 year old women) 🤒Abdominal pain and a palpable, nontender, upper abdominal mass 🩻Well circumscribed, encapsulated, heterogeneous pancreatic lesion with cystic degeneration on CT or MRI 🔬Microscopic features: ▪️Tumors are heterogeneous, with variable admixture of solid and pseudopapillary areas ▪️Solid areas are comprised of uniform cells admixed with capillary sized blood vessels ▪️Pseudopapillae are formed due to tumor cells getting detached from blood vessels forming fibrovascular stalks or rosette-like structures ▪️Stroma usually shows various degrees of hyalinization ➕Beta catenin ➕E-cadherin ➖Chromogranin A #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #pancreas #solidpseudopapillaryneoplasm
Win best Speaker Award Don't miss the chance to Win Best Speaker Award at the 14th Emirates Pathology, Digital Pathology & Cancer Conference from December 17-19, 2024, in Dubai, UAE & Virtual. Register virtually here: https://pathology.universeconferences.com/virtual-registration/ #SurgicalPathology #Pathology #SurgicalSpecimens #PathologyReports #Histopathology #Pathologists #DiagnosticPathology #TissueDiagnosis #CancerDiagnosis #MedicalLaboratory #GrossPathology #MicroscopicPathology #PathologyCases #AnatomicPathology #ClinicalPathology
📌Subacute thyroiditis 📖Granulomatous inflammation of the thyroid gland with characteristic clinical and microscopic findings 🔗Historical name: de Quervain thyroiditis 🤒Clinical features :Fatigue, low grade fever, myalgias, along with neck pain and diffuse goiter 🔬Microscopic features : 🔰Mid stage : ▫️Chronic inflammation: lymphocytes, plasma cells Epithelioid and nonepithelioid macrophages and multinucleated giant cells adjacent to or within disrupted follicles, surround and engulf residual colloid ▫️Well formed granulomata are not seen ▫️Variable degrees of fibrosis #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #thyroid #subacutethyroiditis #dequervainthyroiditis
📌Adenofibroma of ovary depicting fibrous stroma with cyst lined by simple cuboidal epithelium. 🖇️The cysts/ glands form the minor component of the tumour. 🖇️The major component is formed by the fibrous stroma. #pathology #pathologyresidency #pathologyreporting #pathologyreview #pathologyreports #medicine #histology #FemaleGenitalTract #benigntumours #Ovary #adenofibroma
🧩Adenoid cystic carcinoma 🔬Tumor cells arranged in cribriform pattern with perineural invasion #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #parotid #adenoidcysticcarcinoma ❓Which of the following statements is true?
We Are Here For You 24*7🕒🌐 Day Or Night, Rain Or Shine, Count On Us Anytime, Anywhere ! 🌟 Our Dedicated Team Is Here Round The Clock To Assist You With Any Inquiries. Your Satisfaction And Peace Of Mind Are Our Top Priorities. Reach Out To Us Anytime, And Let Us Take Care Of The Rest ! Branch 1 : B. K. In Front Of Cinema, Next To Mamta Medical, S.T. Workshop Road, Mehsana-384002 Branch 2 : Third Floor, M-3 Block, Hubtown, In Front Of New Bus Station, Dr. R. B. In Front Of Shah's New Hospital, Modhera Four Road, Mehsana-384002 Experience Excellence In Diagnostic Services At The Best Pathology Laboratory In Mehsana, As We Take Pride As The Best Laboratory In Mehsana. We Offer The Convenience Of Home Sample Collection In Mehsana. For More Details Call Us At 99096 76024 | 02765 254096. #CustomerService #AlwaysHereForYou #homesamplecollectionservice #bestpathologyinmehsana #fullbodycheckup #laboratory #mehsanacity #mehsana #mojilumehsana #madhuramlaboratory #BestLab #madhurampathologylab #BestLab #bestlab #bodytest #PathologyTesting #LabServices #PathologyReports #pathology #checkup #hubtownmehsana🤙🏻
♦️Pemphigus vulgaris 🔍Caused by IgG or IgA autoantibody against epidermal antigens (commonly desmoglein 1 and desmoglein 3) 🤒Clinical presentation: flaccid bullae or crusted erosions involving skin or mucosa 🧪 Direct immunofluorescence shows intercellular IgG and C3 in the epidermis 🔬Microscopic features: 〰️Suprabasal acantholysis 〰️Basal layer remains attached (tombstone sign) 〰️Intraepidermal vesicles with round acantholytic keratinocytes 〰️Intraepidermal eosinophils and sometimes neutrophils 〰️No significant dyskeratosis #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #skin #pemphigusvulgaris
⭕️Invasive lobular carcinoma-Breast 📝Special subtype of invasive breast carcinoma characterized by discohesive tumor cells arranged in single files or as individual single cells ☢️Ultrasound Hypoechoic mass with spiculated or ill defined margins and posterior acoustic shadowing 🔬Microscopic features : 〰️Tumor cells arranged in single files, cords and single cells ✔️Can be arranged concentrically around normal ducts, giving a targetoid appearance 〰️Tumor cells discohesive, small, monomorphic and lacking marked atypia 〰️Round or notched ovoid nuclei, usually grade 1 or 2 nuclear score 〰️Scant cytoplasm, occasional with intracytoplasmic lumen 〰️Mitosis infrequent ➕Stains: ➕Estrogen receptor (97%) and progesterone receptor (80%) ➕p120 (88%) (cytoplasmic) ➕Beta catenin (42% nuclear and cytoplasmic; 23% retained membranous staining) ➖Stains: E-cadherin (16%) E-cadherin absence or reduction of membranous staining #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #breast #breastcancer #lobularcarcinoma
Difference between chronic bronchitis and emphysema . . . MEDICOSE FEVER OFFICIAL . . . 4th year mbbs special pathology . . #mbbsstudent #MBBS #bds #dpt #medics #ClinicalPathology #Surgery #Medicine #MedicalEducation #MedicalCommunity #Pathology #SurgicalProcedures #MedicalResearch #MedicineInPakistan #SurgicalTechniques #ClinicalCases #MedicineUpdates #PathologyLab #SurgeryLife #MedEd #pathology #MedicalStudents #PathologyFacts #PathologyReports #SurgeryRoom #MedicineField #PathologyConference #SurgicalInnovation #medicalprofessionalslv
🔘A 35-year-old woman with fever, weight loss, weakness and massive hepatosplenomegaly. 🧪In lab data, pancytopenia was observed. ▪️ELISA rapid test was negative for leishmaniosis. ▫️Bone marrow aspiration showed amastigotes within macrophages and outside cells ✅Dx:Visceral Leishmaniosis in Bone Marrow Aspiration #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #bonemarrow #leishmaniosis #amastigotes
Best Pathology Laboratory Provides Best Services in Mehsana. Get Tested Today For A Healthier Tomorrow ! Our Services : 1. Blood Collection For All Age Groups 2. Upgraded Medical Equipment 3. Comprehensive Blood Testing Facilities 4. Spacious Waiting Area 5. 24/7 Availability 6. Home Sample Collection Facility Branch 1 : B. K. In Front Of Cinema, Next To Mamta Medical, S.T. Workshop Road, Mehsana-384002 Branch 2 : Third Floor, M-3 Block, Hubtown, In Front Of New Bus Station, Dr. R. B. In Front Of Shah's New Hospital, Modhera Four Road, Mehsana-384002 Experience Excellence In Diagnostic Services At The Best Pathology Laboratory In Mehsana, As We Take Pride As The Best Laboratory In Mehsana. We Offer The Convenience Of Home Sample Collection In Mehsana. For More Details Call Us At 99096 76024 | 02765 254096. #homesamplecollectionservice #bestpathologyinmehsana #fullbodycheckup #laboratory #mehsanacity #mehsana #mojilumehsana #madhuramlaboratory #BestLab #madhurampathologylab #BestLab #bestlab #bodytest #PathologyTesting #LabServices #PathologyReports #pathology #checkup #hubtownmehsana🤙🏻
✨Angiolymphoid hyperplasia with eosinophilia (ALHE) ✏️A rare, benign vascular neoplasm characterized by proliferation of blood vessels along with inflammatory infiltrate rich in eosinophils 📊Most common in middle aged adults 📍Most common sites are skin and subcutaneous tissue of head and neck, particularly the face, scalp and ear lobes ❓Idiopathic condition 🧪Eosinophilia and elevated IgE levels may be present in patients 🔎Single or multiple, dome shaped, light pink to red brown papules or subcutaneous masses with no specific distinguishing surface features 🔬Microscopic features: 〰️Dermal based lesion with extension into the subcutaneous tissue 〰️Proliferation of vascular channels as nests and cords of endothelial cell proliferations with admixed lymphocytes, plasma cells and eosinophils, accompanied by hemorrhage and proliferation of thick and thin walled blood vessels 〰️Endothelial cells show large vesicular nuclei with acidophilic and sometimes vacuolated cytoplasm, imparting a hobnail appearance #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #skin #angiolymphoidhyperplasiawitheosinophilia #ALHE
♦️Yolk sac tumor 🧪Elevated alpha fetoprotein in 95 - 98% of the cases ☢️Ultrasound: Heterogenous echogenicity, frequently with cystic spaces, ill defined margins and calcifications 📯Endodermal sinus (perivascular) pattern: 🔎This pattern displays a papillary structure called Schiller-Duval body. It consists of a fibrovascular core with a single central thin-walled vessel in a hyalinized stroma surrounded by a one or more layers of cuboidal tumor cells with clear cytoplasm 🚨Schiller-Duval body is a hallmark of YST but is not required for diagnosis #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #testis #testicularmass #yolksactumor #schillerduvalbodies
🔗Secretory meningioma WHO grade 1 🧠 🔬Microscopic features: 💢Eosinophilic round secretions (pseudopsammoma bodies) positive for CEA and PAS 💢Genetically characterized by combined KLF4 and TRAF7 mutations #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #brain #meningioma #secretorymeningioma
🔆Focal segmental glomerulosclerosis (FSGS) ⭕️FSGS is characterized by focal (involving some but not all glomeruli) and segmental (< 100% glomerular tuft involvement with some residual patent glomerular capillaries) sclerosis of glomeruli without underlying immune complex disease 🎨Jones methenamine silver (JMS), periodic acid-Schiff (PAS): highlight glomerular architecture and sclerosis #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #kidneydisease #fsgs #focalsegmentalglomerulosclerosis
📝Essential thrombocythemia 💢Diagnostic criteria for early / prefibrotic essential thrombocythemia: requires either all major criteria or the first 3 major criteria plus the minor criterion ⭕️Major 〽️Criterion #1: sustained platelet count ≥ 450 x 109/L 〽️Criterion #2: megakaryocyte proliferation, large and mature with hyperlobulated nuclei (atypical), little to no granulocyte or erythroid proliferation; very rarely a minor (grade P) increase in reticulin fibers 〽️Criterion #3: does not meet WHO criteria for chronic myeloid leukemia, polycythemia vera, primary myelofibrosis, myelodysplastic syndrome or other myeloid neoplasm 〽️Criterion #4: demonstration of JAK2 or CALR or MPL mutation ⭕️Minor 🔅Presence of a clonal marker 🔅Absence of evidence of reactive thrombocytosis 📌Bone marrow ▪️Normal / mildly hypercellular ▫️Atypical megakaryocytes ▪️Increased number and large atypical forms with deeply lobulated or hyperlobulated nuclei (staghorn nuclear appearance) ▫️Dispersed throughout the marrow with occasional loose clusters; dense clusters are uncommon ▪️No highly bizarre / dysplastic forms, no predominance of small megakaryocytes with monolobulated nuclei ▫️Delicate reticulin fibers (myelofibrosis absent / minimal) but no overt fibrosis (usually grade 1) ▪️Usually normal erythroid and granulocytic proliferation #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #bonemarrow #essentialthrombocythemia
❇️Endometroid adenocarcinoma with squamous differentiation #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #endometrialcancer #endometrialcarcinoma
🌀Myofibroblastoma-Breast benign tumors ➖Well circumscribed, lacks true capsule, rarely infiltrative ➖Bland, uniform, short to elongated spindle cells arranged as short haphazard intersecting fascicles admixed with bands of hyalinized, brightly eosinophilic collagen and variable amounts of fat ➖No more than mild nuclear atypia ➖Mitoses usually absent, atypical mitoses and necrosis absent ➖Mast cells common, perivascular lymphocytic infiltrates on occasion ➖Focal myxoid stromal changes common #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #breastmass #myofibroblastoma
🔘Majocchi’s granuloma 🔘Nodular granulomatous perifolliculitis 🔆Presents as perifollicular pustule/nodule, often at sites of shaving 🔆Fungal organisms surround hair shaft 🔆Often accompanied by dense perifollicular mixed acute, chronic, and/or granulomatous inflammation 💢Fungal organisms highlighted by GMS, PAS 💢Trichophyton rubrum is most common cause (dermatophyte) ⭕️ Ddx: bacterial folliculitis, viral folliculitis, other granulomatous entity #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #skin #majocchisgranuloma #trichophytonrubrum #hairfungal
🎭Atypical tripolar mitosis #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #atypicalmitosis #tripolarmitosis #mercedesbenz
Pacinian corpuscles🤷🏻♀️ #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #paciniancorpuscle
🎯Tubular carcinoma-Breast 📝Special subtype of invasive breast carcinoma with favorable prognosis 🔬Microscopic features: ▪️Invasive breast cancer with infiltrative growth pattern, often with invasion into adipose tissue and with an associated fibrous or desmoplastic stromal response ▪️No myoepithelium surrounding the tubules ▪️> 90% of the tumor is composed of small, ovoid or angulated tubules with open lumina ▪️Tubules are lined by a single layer of epithelial cells with low grade nuclei and sparse mitoses (grade 1) ▪️Tumor cells often have apical cytoplasmic tufting or snouts Cells lining the neoplastic tubules are cuboidal to columnar with uniform, small to intermediate sized nuclei ▪️No significant cytologic atypia, multilayering or high mitotic activity 🔔Tumor cells are ER positive and HER2 negative #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #breast #breastcarcinoma #tubularcarcinoma
⭕️Sebaceous adenoma 📌Well circumscribed, nodular growth of lobules consist of admixture of basaloid cells and mature sebocytes 📌Some lobules may communicate directly with the surface epithelium 📌Basaloid cells are usually located at the periphery of lobules and sebaceous cells with intracytoplasmic lipid vacuoles, which are usually located at the center of lobules 📌Basaloid cells are composed of expanded germinative layer, with more than the normal 2 cell layers seen in mature sebaceous glands or sebaceous hyperplasia but still less than 50% of the tumor volume #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #skin #sebaceousadenoma
⭕️Cutaneous mixed tumor ⭕️Benign adnexal tumor of the skin composed of mesenchymal and sweat gland components #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #skin #cutaneousmixedtumor #chondroidsyringoma
📌Hailey-Hailey disease ➖Suprabasilar and intraepidermal clefting ➖Acantholysis of keratinocytes resembling dilapidated brick wall ➖Epidermal hyperplasia ➖No pronounced dyskeratosis but dyskeratotic keratinocytes have well defined nucleus and preserved cytoplasm (unlike pemphigus vulgaris) ➖Dermis shows variable chronic inflammatory infiltrate Parakeratotic crust may contain neutrophils and bacteria #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #skin #haileyhaileydisease #pemphigus
🎯Collagenous spherulosis-Breast ➰Round spaces filled with acellular pink basement membrane material (spherules) ➰Spherules measure 20 - 100 μm in diameter ➰Center of the spherules may be transparent but thin rim of basement membrane material always present ➰Myoepithelial cells are uniformly present at the periphery of involved glands 🚨Majority associated with benign proliferative lesions, mostly intraductal papilloma #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #breast #collagenousspherulosis
➰Scabies (mite) 👁️🗨️Superficial perivascular lymphoeosinophilic infiltrate with histiocytes and possible neutrophils 👁️🗨️Possible epidermal spongiosis with or without features of excoriation (ulceration, erosion) and crust 👁️🗨️CD30+ infiltrate possible #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #skin #scabies #mite
🔷Molluscum contagiosum 🔹Henderson-Patterson bodies 🔹Eosinophilic molluscum bodies which become more basophilic based on the location in the epidermal layers #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #molluscumcontagiosum #skin
🔮Plasma cell myeloma (multiple myeloma) 🔬Interstitial clusters, nodules or sheets of plasma cells 🔬IHC to quantify plasma cells (CD138), stains for Ig kappa and lambda to establish clonality #pathologistsassistant #pathology #pathologyresidency #pathologyreview #pathologycasereporting #pathologyreports #medical #medicine #medicalstudent #medicalschool #histology #histologylab #histologyclass #pathologyskills #bonemarrow #plasmacell #multiplemyeloma #plasmacelldyscrasia